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pp 135–139
KU-0063794 inhibits the phosphorylation of mTORC1 at Ser2448 and mTORC2 at Ser2481 in a dose-dependent and time-dependent manner
6-dihydropyridine-3-carboxamide
InChiKey: WQZGKKKJIJFFOK-GASJEMHNSA-N
Leflunomide Catalog No.:M7673-10 pp 135–139Leflunomide (original brand name Arava) is an immunosuppressive disease modifying antirheumatic drug (DMARD), used in active moderate to severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. Product information CAS Number: 75706 12 6 Molecular Weight: 270. 21 Formula: C12H9F3N2O2 Synonym: Arava Leflunomidum HWA 486 Chemical Name: 5 methyl N [4
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